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歷 年 稿 件 內 容
 
*類別: A組-鏡檢、血液、血庫
* 姓名: 徐文通
投稿種類: 壁報
*中文投稿標題: T2DM患者的Monocyte和Adiponectin表現探討
*中文作者姓名列: 徐文通1、楊登和1、2、許宏彰3、曹其森4、張勝皇5
*中文服務單位: 國軍台中總醫院檢驗科1,內科部2,清泉醫院3,衛福部疾管署4,衛福部草屯療養院5
*英文投稿標題: Monocyte and Adiponectin in Type 2 Diabetes Mellitus Patients
*英文作者姓名列: Hsu Wen-Tung1; Yang Deng-Ho 1、2; Hsu Hung-Chang3; Tsao Chi-Sen4 , Chang Sheng-Huang5
*英文服務單位: Division of Laboratory1, Department of Internal Medicine2, Taichung Armed Force General Hospital, Ching Chyuan Hospital3, Center for Research, Diagnostics and Vaccine Development,Centers for Disease Control4, Ministry of Health and Welfare, Tsaotun Psychiatric Center, Ministry of Health and Welfare5
* 投稿摘要: Monocyte could play a major role in the invasion of the pancreas and leads to insulin resistance in type 2 diabetes mellitus(T2DM) patients. On the other hand, Hypoadiponectinemia is reported to be associated with metabolic syndrome. This study was to understand the expression of Monocyte and Adiponectin in T2DM patients. 46 T2DM patients and 39 patients without DM were inclued in this study. T2DM patients were divied to two subgroup; group I (HOMA-IR<2.6) and group II (HOMA-IR≧2.6). Insulin resistance was calculated using the HOMA-IR formula. Result was divided by the average concentration of the control group and the ratio was taken as standardized level and data were analyzed by t test. The standardized level of Monocyte in patients with T2DM (1.18±0.38 fold) showed highly significant differences of control group(**P=0.005); but the level of Adiponectin in patients with T2DM (0.77±0.23 fold) were lower than control patients, with lowly significant differences of control group(**P=0.003). The level of subgroup II with Monocyte (1.24±0.42 fold) were higher than control and subgroup I patients (1.08±0.29 fold; **p =0.002). It is similar to before, the level of subgroup II with Adiponectin (0.75±0.23 fold) when compared to control group were lower than subgroup I (0.80±0.25 fold), showed significant of control patients (**p =0.007). The highest of Monocyte accompanied hypoadiponectinemia may cause increase level of HOMA-IR that revealed insulin resistance in patients with T2DM. However, still need further studied to confirm.
*關鍵字1 : Type 2 diabetes mellitus
*關鍵字2 : Monocyte
*關鍵字3 : Adiponectin
*關鍵字4 :
*關鍵字5 :
* 服務機關:
* 第一作者: 徐文通
* 身分字號: *****46482
其他投稿作者: 楊登和
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其他投稿作者: 許宏彰
身分字號: *****22557
其他投稿作者: 曹其森
身分字號: *****02711
其他投稿作者: 張勝皇
身分字號: *****20464
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審查委員意見: 無意見
審查委員意見: OK
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