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歷 年 稿 件 內 容
 
*類別： C組-生化、血清免疫
* 姓名： 劉秋菁
投稿種類： 壁報
*中文投稿標題： 非酵素電化學式尿酸檢驗方法干擾性與臨床比對之研究
*中文作者姓名列： 劉秋菁 、廖儷婷 、楊婷雅 、吳太光、王炯中
*中文服務單位： 台北市立萬芳醫院委託財團法人台北醫學大學辦理
*英文投稿標題： The interference and clinical comparison study for an electrochemical non-enzymatic uric acid detection method
*英文作者姓名列： Chiu-Ching Liu;Li-Ting Liao;Ting-Ya Yang;Tai-Guang Wu;Giueng-Chueng Wang
*英文服務單位： Department of Laboratory Medicine, Wan Fang Hospital, Taipei Medical University
* 投稿摘要： Research background It became important of uric acid measurement and only non-enzymatic method is available for over the counter usage. However, interfered by many medicines and biological material have not been evaluated for non-enzymatic uric acid methods. Objective The purpose of this study was to evaluate the performance of a commercial available uric acid monitoring system. Materials and Methods BeneCheck PLUS multi-monitoring system for glucose, uric acid and total cholesterol was used to evaluate the uric acid measurement function such as precision, interference, hematocrit, hemolysis of blood effect and clinical validation. Results The precision of three levels of venous blood samples and coefficient variation were 45 mg/l, 2.9%, 72 mg/l, 3.1% and 135 mg/l, 2.0% respectively. Sample with 30% and 55% of hematocrit were acceptable when measured with BeneCheck. Acetaminophen showed a high interference (66.8%/200 mg/l test level) but with a 13.7%/30 mg/l interference. Hemolysis blood samples bias% was within -3.1% for BeneCheck but was -45.9% for the sample with 75 g/l lysed hemoglobin by centralized instrument. Total 187 samples with uric acid range from 40 mg/l to 123 mg/l were collected and 86.1% and 95.2% of tests within ±15% and ±20 % bias%. Conclusion Both finger and venous blood samples were suitable for uric acid measurement by BeneCheck. Based on the results of precision, interference and accuracy study, we concluded that BeneCheck uric acid monitoring system was suitable for users or professionals to monitoring their uric acid concentration or screening uric acid of patients.
*關鍵字1 ： uric acid
*關鍵字2 ： Non-enzymatic method
*關鍵字3 ： interference
*關鍵字4 ： acetaminophen
*關鍵字5 ： Hemolysis
* 服務機關：
* 第一作者： 劉秋菁
* 身分字號： *****07983
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