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歷 年 稿 件 內 容
 
*類別： C組-生化、血清免疫
* 姓名： 林碧珍
投稿種類： 壁報
*中文投稿標題： 探討第二型糖尿病糖化血色素變化在 視網膜病變嚴重程度之間的相關性
*中文作者姓名列： 林碧珍1、梁景超2、劉志龍3、賴盈如1、蕭璧容1
*中文服務單位： 高雄醫學大學附設中和紀念醫院內分泌新陳代謝內科1,高雄市立旗津醫院 檢驗組2,高雄市立大同醫院眼科3
*英文投稿標題： Association between HbA1c and pathogenesis of diabetic retinopathy in type 2 diabetes
*英文作者姓名列： Lin Pi-Chen1;Liang Ching-Chao2;Liu Chih-Long3;Lai Ying-Ju1;Hsiao Pi-Jung1
*英文服務單位： Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital1;Department of Laboratory Medicine, Kaohsiung Municipal Cijin Hospital2;Department of Ophthalmology,Kaohsiung Municipal Ta-Tung
* 投稿摘要： Background: Diabetic retinopathy is due to microvascular pathogenesis-induced hypoxemias and altered osmosis on retina. Furthermore, hypoxemias and altered osmosis result in angiogenesis and macular edema to occur blindness in patients with diabetic retinopathy Object: In study, the association between HbA1c and pathogenesis of diabetic retinopathy was investigated in type 2 diabetes. Methods: The biochemical data and images of ocular funduscopy of diabetes from clinic of metabolism and endocrinology, or healthy people form physical examination were analyzed by SPSS 20.0 statistic analysis. Results: In this study, we collected biochemical data and images of ocular funduscopy of 511 diabetes (average is 60.44±14.19 years). The patients in this study were 79.6% type 2 diabetes including 40.5% (HbA1<6.5%), 26% (HbA1c 6.5-7.9%), 10.9% (HbA1c 8-10%), and 5.5% (HbA1c>10%). The analysis of diabetic retinopathy showed 48.9% (HbA1c<6.5%), 31.4% (HbA1c 6.5-7.9%), 13.2% (HbA1c 8-10%), and 6.6% (HbA1c>10%) in No Apparent Retinopathy; 6.2% (HbA1c<6.5%), 50.0% (HbA1c 6.5-7.9%), 12.5% (HbA1c 8-10%), and 31.2% (HbA1c>10%) in Mild Non-Proliferative Diabetic Retinopathy; 18.7% (HbA1c<6.5%), 42.7% (HbA1c 6.5-7.9%), 21.3% (HbA1c 8-10%), and 17.3% (HbA1c>10%) in Moderate Non-Proliferative Diabetic Retinopathy; 8.3% (HbA1c<6.5%), 41.7% (HbA1c 6.5-7.9%), 33.3% (HbA1c 8-10%), and 16.7 % (HbA1c>10%) in Severe Non-Proliferative Diabetic Retinopathy; 42.9% (HbA1c 6.5-7.9%), 14.3% (HbA1c 8-10%), and 42.9 % (HbA1c>10%) in Proliferative Diabetic Retinopathy. These results presented significance (p<0.05) in Chi-Square Test. Conclusion: Diabetic Retinopathy is common complication of diabetes and significantly causes blindness. This study indicated serious pathogenesis of diabetic retinopathy was due to hyperglycemia companied with hypertension, hyperlipidemia, or nephropathy. In type 1 or type 2 diabetes (history >10 years), the 50% patients expresses pathogenesis of diabetic retinopathy in eyes. Diabetes occur blindness by 25 times compared with healthy people so that diabetes must be cured by doctors in early stage of diabetic pathogenesis and control blood glucose, blood pressure, and blood fat to prevent diabetic retinopathy .
*關鍵字1 ： Diabetic retinopathy
*關鍵字2 ： HbA1c
*關鍵字3 ： Type 2 diabetes
*關鍵字4 ： blindness
*關鍵字5 ： keyword
* 服務機關：
* 第一作者： 林碧珍
* 身分字號： *****94227
其他投稿作者： 梁景超
身分字號： *****42730
其他投稿作者： 劉金龍
身分字號： *****67452
其他投稿作者： 賴盈如
身分字號： *****34876
其他投稿作者： 蕭璧容
身分字號： *****92074
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