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歷 年 稿 件 內 容
 
*類別: B組-微生物、病毒
* 姓名: 陳建源
投稿種類:
*中文投稿標題: 台灣北部某區域醫院對於廣泛耐藥抗藥性菌株使用快速診斷試劑偵測克雷伯菌碳青黴烯酶的情形
*中文作者姓名列: 陳建源
*中文服務單位: 衛生福利部臺北醫院
*英文投稿標題: Rapid identification of KPC carbapenemase on extensively drug-resistant bacterial colony in one Regional Teaching Hospital of Northern Taiwan.
*英文作者姓名列: Chen Jiann-yuan
*英文服務單位: Taipei Hospital, Ministry of Health and Welfare, Taiwan, R.O.C.
* 投稿摘要: Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality. KPCs are an important mechanism of resistance for an increasingly wide range of Gram-negative bacteria and are no longer limited to K.pneumoniae. KPC-producing bacteria are often resistance to the carbapenem antibiotic, Antimicrobial Agent phenotypic tests already exist for detection of carbapenemase but these tests are time-consuming and do not allow identification of KPC. Molecular identification tests need dedicated environment, skilled people and are expensive. This Rapid diagnostic test(KPC K-SeT) is aimed to the detection of KPC on a single colony from a carbapenemase producing enterobacteriaceae (CPE) within 20 minutes.It is a kind of a method can quickly know the KPC results. When bacterial the drug sensitivity of Cefepime(FEP) and imipenem (IPM) are Resistance called Extensive Drug-Resistant Organism (XDRO). Total 60 XDRO specimen collection including 56 K.pneumonia (72.2%), 3 E.coli (22.2%), and 1 K. oxytoca (5.5%). Positive and Negative results, respectively 31 and 29. All KPC positive for K. pneumoniae yielded.Positive and Negative results, respectively 31(55.4%) and 25(44.6%). Rapid identification of KPC is of upmost importance to improve both patient therapy and control of the spread of such antibiotic resistance in hospitals. This study is also the first experiment report to detect KPC by rapid test in Taiwan hospital microbiology unit.
*關鍵字1 : Klebsiella Pneumoniae Carbapenemase (KPC)
*關鍵字2 : Carbapenemase Producing Enterobacteriaceae (CPE)
*關鍵字3 : Rapid diagnostic test
*關鍵字4 : Extensive Drug-Resistant Organism (XDRO)
*關鍵字5 : Rapid identification
* 服務機關:
* 第一作者: 陳建源
* 身分字號: *****64352
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