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歷 年 稿 件 內 容
 
*類別:
* 姓名: 楊順發
投稿種類: 壁報
*中文投稿標題: Elevated plasma Pentraxin 3 protein in patients with community-acquired pneumonia
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* 投稿摘要: Pentraxin 3 (PTX3) plays an important role in innate immune responses and in inflammation disease. The aim of this study was to investigate the diagnostic and prognostic potential of PTX3 in community-acquired pneumonia (CAP) and correlate it with the severity and outcome of CAP. In this study, we collected blood specimens from 60 patients with CAP before and after treatment and 60 healthy controls and measured the plasma levels of PTX3 using enzyme-linked immunosorbent assay (ELISA) kits. We found that the plasma level of PTX3 expression was elevated in CAP patients compared with healthy controls, and decreased significantly after they received treatment. Plasma PTX3 concentration was significantly correlated with white blood cell (WBC) and neutrophil counts in patients with CAP (p<0.01). In conclusion, elevated plasma PTX3 could be a biological marker for the diagnosis and to be a new strategy for target therapy of community-acquired pneumonia.
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* 第一作者: 楊順發
* 身分字號: *****08094
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