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歷 年 稿 件 內 容
 
*類別:
* 姓名: 呂旭峰
投稿種類: 壁報
*中文投稿標題: Medicinal Mushroom Agaricus blazei Murill Extract of Oral Administration Enhances the Non-Specific Immune Activities in BALB/c Mice
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* 投稿摘要: Agaricus blazei Murill (AbM) is used traditionally against a range of diseases. In this study we evaluated the immunomodulatory effects of AbM. For the non-specific immune response experiments, a total of 40 female BALB/c mice were divided into control (group 1) and experimental (second to fourth groups) groups of ten animals each. Groups 2, 3 and 4 were orally administered high (819 mg/kg), medium (273 mg/kg) and low (136.5 mg/kg) doses of AbM daily for 6 weeks and then six parameters related to non-specific immune response were detected. In the current study, we found that feeding mice with AbM extract increased the levels of IgG in sera and promoted the phagocytosis from the peritoneal macrophages and did elevate the activity of NK cells. We also found that the levels of IL-2in splenocytes were increasing in high dose treatment and F-was in medium dose. The levels of IL-4were reduced or unchanged. These results provide evidence that AbM can modulate innate immunity.
*關鍵字1 : Agaricus blazei Murill
*關鍵字2 : immunomodulatory effects
*關鍵字3 : non-specific immune response
*關鍵字4 : phagocytosis
*關鍵字5 : NK cells
* 服務機關:
* 第一作者: 劉德民
* 身分字號: *****42257
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開啟檔案
審查委員意見: 建議改投"血清免疫"組
審查委員意見: 本篇是評估巴西蘑菇對老鼠免疫力的分析,建議轉至"免疫"組
主任委員意見: 無意見
 
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