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歷 年 稿 件 內 容
 
*類別:
* 姓名: 李元民
投稿種類: 壁報
*中文投稿標題: A false-negative serology results in a HIV infected case
*中文作者姓名列:
*中文服務單位:
*英文投稿標題:
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*英文服務單位:
* 投稿摘要: Background. For assays of HIV infection, both false-negative and false-positive results have profound implications. A 27 years old male was attended to our emergency department with fever, sore throat and leukopenia. Physician reported the patient with risk behavior was suspected HIV viral infection. Methods. HIV Screening test was performed with a 4th generation immunoassay Abbott Architect I1000 ( HIV ½ Ag/Ab Combo) and Roche Diagnostics Elecsys E170 (HIV½ Ag/Ab Combo). To establish HIV infection was used Western blot results. HIV-1 subtypes were determined using nested polymerase chain reactions with multiplex primers and phylogenetic analyses. Results. The discrepancy HIV EIA results were founded between Abbott Architect (reaction: 24.62 S/Co, Positive) and Roche Elecsys (Non-reaction: 0.3 S/Co, Negative).However, the Western blot confirmed results was Positive. The HIV strain was determined subtype B by multiplex PCR and Phylogenetic analyses. Conclusions. The inability to detect HIV during early infection (window period) remains a critical limitation in HIV testing. When diagnosis of HIV infection that consideration contact history risk, risk behavior and prevalence rates. The sample with HIV positive results in screening test that should be subject to additional testing including NAT and Western blot confirmatory testing to determine.
*關鍵字1 : HIV test
*關鍵字2 : multiplex PCR
*關鍵字3 : Phylogenetic analyses
*關鍵字4 : HIV Screening test
*關鍵字5 : false-negative
* 服務機關:
* 第一作者: 陳正雄
* 身分字號: *****61650
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